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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
19.7
Human Site:
S502
Identified Species:
33.33
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
S502
L
A
I
D
V
L
D
S
P
Q
A
V
R
R
S
Chimpanzee
Pan troglodytes
XP_508221
618
67613
S592
L
A
I
D
V
L
D
S
P
Q
A
V
R
R
S
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
N465
K
D
T
R
S
I
E
N
V
V
Q
D
L
R
S
Dog
Lupus familis
XP_855547
495
55650
S469
L
A
I
D
V
L
D
S
P
H
A
I
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
S472
L
A
I
D
V
L
D
S
P
H
T
I
R
R
S
Rat
Rattus norvegicus
P04177
498
55948
S472
L
A
I
D
V
L
D
S
P
H
T
I
Q
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
N542
Q
R
I
E
V
L
D
N
T
D
Q
L
K
I
L
Chicken
Gallus gallus
P70080
445
51121
S420
K
D
T
K
S
I
A
S
V
V
N
E
L
R
H
Frog
Xenopus laevis
Q92142
481
55388
M456
K
D
T
K
S
I
A
M
V
V
R
E
L
R
H
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
P464
S
I
E
V
L
D
N
P
L
K
I
Q
K
G
L
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
R451
E
V
L
D
Q
P
C
R
I
Q
N
A
L
S
K
Fruit Fly
Dros. melanogaster
P18459
579
65977
S550
E
R
V
E
V
L
D
S
V
D
K
L
E
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
R432
D
K
V
A
A
L
Q
R
L
A
R
D
I
R
S
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
K496
Q
S
I
Q
V
I
D
K
V
D
K
L
R
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
13.3
86.6
N.A.
80
73.3
N.A.
26.6
13.3
6.6
0
13.3
26.6
N.A.
20
26.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
86.6
86.6
N.A.
53.3
20
13.3
26.6
20
46.6
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
0
8
8
0
15
0
0
8
22
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
22
0
43
0
8
58
0
0
22
0
15
0
8
0
% D
% Glu:
15
0
8
15
0
0
8
0
0
0
0
15
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
15
% H
% Ile:
0
8
50
0
0
29
0
0
8
0
8
22
8
8
0
% I
% Lys:
22
8
0
15
0
0
0
8
0
8
15
0
15
0
8
% K
% Leu:
36
0
8
0
8
58
0
0
15
0
0
22
29
0
22
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
15
0
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
36
0
0
0
0
0
0
% P
% Gln:
15
0
0
8
8
0
8
0
0
22
15
8
8
0
0
% Q
% Arg:
0
15
0
8
0
0
0
15
0
0
15
0
36
65
0
% R
% Ser:
8
8
0
0
22
0
0
50
0
0
0
0
0
8
50
% S
% Thr:
0
0
22
0
0
0
0
0
8
0
15
0
0
8
0
% T
% Val:
0
8
15
8
58
0
0
0
36
22
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _